MESDC2 抗体 (Internal Region)
Quick Overview for MESDC2 抗体 (Internal Region) (ABIN6263227)
抗原
See all MESDC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- MESDC2 Antibody detects endogenous levels of total MESDC2.
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预测反应
- Zebrafish,Bovine,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human MESDC2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Mesoderm Development Candidate 2 (MESDC2) (AA 1-234) antibody
MESDC2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mesoderm Development Candidate 2 (MESDC2) (AA 203-234), (C-Term) antibodyMESDC2 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Mesoderm Development Candidate 2 (MESDC2) antibodyMESDC2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mesoderm Development Candidate 2 (MESDC2) (AA 1-234) antibodyMESDC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- MESDC2 (Mesoderm Development Candidate 2 (MESDC2))
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别名
- MESDC2
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背景
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Description: Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 (By similarity). May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells (By similarity).
Gene: MESDC2
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分子量
- 26 kDa
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基因ID
- 23184
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UniProt
- Q14696
抗原
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