MCM8 抗体 (C-Term)
Quick Overview for MCM8 抗体 (C-Term) (ABIN6263168)
抗原
See all MCM8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- MCM8 Antibody detects endogenous levels of total MCM8.
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预测反应
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human MCM8, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Minichromosome Maintenance Deficient 8 (MCM8) (C-Term) antibody
MCM8 适用: 人, 大鼠, 小鼠, Cow, 马, 豚鼠, 兔, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 8 (MCM8) (AA 646-735) antibodyMCM8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F9 unconjugated
anti-Minichromosome Maintenance Deficient 8 (MCM8) (AA 717-766) antibodyMCM8 适用: 人, 大鼠, 小鼠, Cow, 马, 豚鼠, 兔, Pig, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 8 (MCM8) (AA 1-67) antibodyMCM8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 8 (MCM8) (AA 144-193) antibodyMCM8 适用: 人, 小鼠, Cow, 马, Pig, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 8 (MCM8) (AA 144-193) antibodyMCM8 适用: 人, 大鼠, 小鼠, Cow, 马, Pig, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 8 (MCM8) (AA 71-120) antibodyMCM8 适用: 人, 大鼠, 小鼠, 马, 豚鼠, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 8 (MCM8) (AA 591-840) antibodyMCM8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 8 (MCM8) (N-Term) antibodyMCM8 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 8 (MCM8) (C-Term) antibodyMCM8 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
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别名
- MCM8
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背景
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Description: Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. May also play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G1 phase by recruiting CDC6 to the origin recognition complex (ORC). Binds chromatin throughout the cell cycle.
Gene: MCM8
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分子量
- 94 kDa
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基因ID
- 84515
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UniProt
- Q9UJA3
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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