MBNL1 抗体 (C-Term)
Quick Overview for MBNL1 抗体 (C-Term) (ABIN6263151)
抗原
See all MBNL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- MBNL1 Antibody detects endogenous levels of total MBNL1.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human MBNL1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Muscleblind-like Protein 1 (MBNL1) (AA 1-382) antibody
MBNL1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (AA 1-383) antibodyMBNL1 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (Middle Region) antibodyMBNL1 适用: 人, 大鼠, 小鼠, 犬, 马, Pig, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (C-Term) antibodyMBNL1 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (AA 1-382) antibodyMBNL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (AA 1-343) antibodyMBNL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (AA 211-260) antibodyMBNL1 适用: 人, 大鼠, 犬, 马, Pig, 兔, 斑马鱼, 猴, Bat, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (AA 1-382) antibodyMBNL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) antibodyMBNL1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) antibodyMBNL1 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
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别名
- MBNL1
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背景
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Description: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.
Gene: MBNL1
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分子量
- 42 kDa
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基因ID
- 4154
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UniProt
- Q9NR56
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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