MAG 抗体 (C-Term)
Quick Overview for MAG 抗体 (C-Term) (ABIN6263053)
抗原
See all MAG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- MAG Antibody detects endogenous levels of total MAG.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human MAG, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Myelin Associated Glycoprotein (MAG) (AA 133-237) antibody
MAG 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 25-516) antibodyMAG 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 119-208) antibodyMAG 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 439-466) antibodyMAG 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal RB21439 unconjugated
anti-Myelin Associated Glycoprotein (MAG) antibodyMAG 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 114-132), (N-Term) antibodyMAG 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 501-582) antibodyMAG 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 551-626) antibodyMAG 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 119-209) antibodyMAG 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-Myelin Associated Glycoprotein (MAG) (C-Term) antibodyMAG 适用: 人, 大鼠 WB, IHC, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- MAG (Myelin Associated Glycoprotein (MAG))
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别名
- MAG
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背景
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Description: Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). Not required for initial myelination, but seems to play a role in the maintenance of normal axon myelination. Protects motoneurons against apoptosis, also after injury, protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. Required to prevent degeneration of myelinated axons in adults, this probably depends on binding to gangliosides on the axon cell membrane (By similarity). Negative regulator of neurite outgrowth, in dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides. In cerebellar granule cells the inhibition is mediated primarily via binding to neuronal gangliosides. In sensory neurons, inhibition of neurite extension depends only partially on RTN4R, RTN4RL2 and gangliosides. Inhibits axon longitudinal growth (By similarity). Inhibits axon outgrowth by binding to RTN4R (By similarity). Preferentially binds to alpha-2,3-linked sialic acid. Binds ganglioside Gt1b (By similarity).
Gene: MAG
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分子量
- 63 kDa.
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基因ID
- 4099
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UniProt
- P20916
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途径
- Neurotrophin Signaling Pathway
抗原
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