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MAFB 抗体 (C-Term)

MAFB 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263052
发货至: 中国
  • 抗原 See all MAFB 抗体
    MAFB (Transcription Factor MafB (MAFB))
    抗原表位
    • 10
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 38
    • 13
    • 12
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 36
    • 2
    克隆类型
    • 35
    • 3
    多克隆
    标记
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAFB antibody is un-conjugated
    应用范围
    • 28
    • 16
    • 14
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    MAFB Antibody detects endogenous levels of total MAFB.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MAFB, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product MAFB Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    MAFB (Transcription Factor MafB (MAFB))
    别名
    MAFB (MAFB 产品)
    别名
    MAFB antibody, krml antibody, Maf-B antibody, XMafB antibody, kreisler antibody, MGC108453 antibody, valentino antibody, KRML antibody, MCTO antibody, Krml antibody, b-maf antibody, kr antibody, mafb antibody, val antibody, wu:fc22d11 antibody, wu:fj82a09 antibody, Kreisler antibody, Krml1 antibody, MAF bZIP transcription factor B antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B S homeolog antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) antibody, MAFB antibody, mafb antibody, mafb.S antibody, Mafb antibody, mafba antibody
    背景

    Description: Acts as a transcriptional activator or repressor (PubMed:27181683). Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.

    Gene: MAFB

    分子量
    36 kDa
    基因ID
    9935
    UniProt
    Q9Y5Q3
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