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MAFB 抗体 (C-Term)

This anti-MAFB antibody is a 兔 多克隆 antibody detecting MAFB in WB, ELISA 和 IHC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6263052
发货至: 中国

Quick Overview for MAFB 抗体 (C-Term) (ABIN6263052)

抗原

See all MAFB 抗体
MAFB (Transcription Factor MafB (MAFB))

适用

  • 36
  • 13
  • 12
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 34
  • 2

克隆类型

  • 33
  • 3
多克隆

标记

  • 19
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MAFB antibody is un-conjugated

应用范围

  • 26
  • 14
  • 12
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 10
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    MAFB Antibody detects endogenous levels of total MAFB.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human MAFB, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    MAFB (Transcription Factor MafB (MAFB))

    别名

    MAFB

    背景

    Description: Acts as a transcriptional activator or repressor (PubMed:27181683). Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.

    Gene: MAFB

    分子量

    36 kDa

    基因ID

    9935

    UniProt

    Q9Y5Q3
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