Galectin 9 抗体 (Internal Region)
Quick Overview for Galectin 9 抗体 (Internal Region) (ABIN6262950)
抗原
See all Galectin 9 (LGALS9) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- Galectin-9 Antibody detects endogenous levels of total Galectin-9.
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预测反应
- Pig,Bovine
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Galectin-9, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) (AA 225-353) antibody
LGALS9 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) (AA 1-323) antibodyLGALS9 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) (AA 51-150) antibodyLGALS9 适用: 人, 小鼠 WB, ELISA, FACS, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) (AA 101-180) antibodyLGALS9 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) (AA 1-323) antibodyLGALS9 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) (AA 1-240) antibodyLGALS9 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) (AA 254-355) antibodyLGALS9 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) (Internal Region) antibodyLGALS9 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) (AA 194-322) antibodyLGALS9 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) (Center) antibodyLGALS9 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000C, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))
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别名
- LGALS9
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背景
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Description: Binds galactosides (PubMed:18005988). Has high affinity for the Forssman pentasaccharide (PubMed:18005988). Ligand for HAVCR2/TIM3 (PubMed:16286920). Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death (PubMed:16286920). Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth (By similarity). Ligand for P4HB, the interaction retains P4HB at the cell surface of Th2 T-helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration (PubMed:21670307). Ligand for CD44, the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity). Promotes ability of mesenchymal stromal cells to suppress T-cell proliferation (PubMed:23817958). Expands regulatory T-cells and induces cytotoxic T-cell apoptosis following virus infection (PubMed:20209097). Activates ERK1/2 phosphorylation inducing cytokine (IL-6, IL-8, IL-12) and chemokine (CCL2) production in mast and dendritic cells (PubMed:24465902, PubMed:16116184). Inhibits degranulation and induces apoptosis of mast cells (PubMed:24465902). Induces maturation and migration of dendritic cells (PubMed:25754930, PubMed:16116184). Inhibits natural killer (NK) cell function (PubMed:23408620). Can transform NK cell phenotype from peripheral to decidual during pregnancy (PubMed:25578313). Astrocyte derived galectin-9 enhances microglial TNF production (By similarity). May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. May provide the molecular basis for urate flux across cell membranes, allowing urate that is formed during purine metabolism to efflux from cells and serving as an electrogenic transporter that plays an important role in renal and gastrointestinal urate excretion (By similarity). Highly selective to the anion urate (By similarity).
Gene: LGALS9
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分子量
- 40 kDa
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基因ID
- 3965
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UniProt
- O00182
抗原
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