LCAT 抗体 (C-Term)
Quick Overview for LCAT 抗体 (C-Term) (ABIN6262927)
抗原
See all LCAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- LCAT Antibody detects endogenous levels of total LCAT.
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预测反应
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human LCAT, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Lecithin-Cholesterol Acyltransferase (LCAT) (AA 290-433) antibody
LCAT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lecithin-Cholesterol Acyltransferase (LCAT) (AA 290-432) antibodyLCAT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lecithin-Cholesterol Acyltransferase (LCAT) (AA 41-210) antibodyLCAT 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lecithin-Cholesterol Acyltransferase (LCAT) (C-Term) antibodyLCAT 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lecithin-Cholesterol Acyltransferase (LCAT) (AA 151-250) antibodyLCAT 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lecithin-Cholesterol Acyltransferase (LCAT) (AA 41-210) antibodyLCAT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lecithin-Cholesterol Acyltransferase (LCAT) (AA 290-433) antibodyLCAT 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Lecithin-Cholesterol Acyltransferase (LCAT) (AA 98-197) antibodyLCAT 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4A9 unconjugated
anti-Lecithin-Cholesterol Acyltransferase (LCAT) (AA 285-313) antibodyLCAT 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB23365 unconjugated
anti-Lecithin-Cholesterol Acyltransferase (LCAT) (AA 292-321), (Middle Region) antibodyLCAT 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))
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别名
- LCAT
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背景
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Description: Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs) (PubMed:10329423, PubMed:19065001, PubMed:26195816). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines (PubMed:8820107). Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms (PubMed:10722751).
Gene: LCAT
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分子量
- 50 kDa
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基因ID
- 3931
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UniProt
- P04180
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途径
- Lipid Metabolism
抗原
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