KPNA1 抗体 (N-Term)
Quick Overview for KPNA1 抗体 (N-Term) (ABIN6262862)
抗原
See all KPNA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- KPNA1 Antibody detects endogenous levels of total KPNA1.
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预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human KPNA1, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 1-300) antibody
KPNA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 1-538) antibodyKPNA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A4-1B5 unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 1-538) antibodyKPNA1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 1-538) antibodyKPNA1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 1-538) antibodyKPNA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 239-506) antibodyKPNA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 8-538) antibodyKPNA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 1-539) antibodyKPNA1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2A4-1B5 unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (N-Term) antibodyKPNA1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig, Bat, 小鸡, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 74-123) antibodyKPNA1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Pig, Bat, 小鸡, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
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别名
- KPNA1
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背景
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Description: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.
Gene: KPNA1
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分子量
- 60kDa
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基因ID
- 3836
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UniProt
- P52294
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途径
- M Phase, Protein targeting to Nucleus
抗原
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