KRT17 抗体 (C-Term)
Quick Overview for KRT17 抗体 (C-Term) (ABIN6262776)
抗原
See all KRT17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Cytokeratin 17 Antibody detects endogenous levels of total Cytokeratin 17.
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预测反应
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Cytokeratin 17, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Keratin 17 (KRT17) antibody
KRT17 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) (AA 252-393) antibodyKRT17 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) (AA 1-432) antibodyKRT17 适用: 人 WB, IF, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 2D4-1G9 unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠 WB, IHC, FACS, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal E3 unconjugated
anti-Keratin 17 (KRT17) (AA 133-432) antibodyKRT17 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠, Cow, Pig, 山羊 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal SPM560 unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 3B12 unconjugated
anti-Keratin 17 (KRT17) (C-Term) antibodyKRT17 适用: 人, 大鼠, 小鼠, Cow, Pig, 犬, 兔, 绵羊, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 1B12 unconjugated
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应用备注
- WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- KRT17 (Keratin 17 (KRT17))
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别名
- KRT17
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背景
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Description: Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (By similarity). May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
Gene: KRT17
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分子量
- 48kDa
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基因ID
- 3872
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UniProt
- Q04695
抗原
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