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ITGA4 抗体 (C-Term)

Name: ITGA4 抗体 (C-Term)
SKU: ABIN6262681
Availability: OutOfStock

This anti-ITGA4 antibody is a 兔多克隆 antibody detecting ITGA4 in WB, IHC 和 ELISA. Suitable for 人, 小鼠和大鼠.

Western blot analysis of Jurkat lysate using ITGA4 antibody. (ITGA4 抗体 (C-Term))

ABIN6276405 at 1/100 staining Human pancreas tissue by IHC-P. (ITGA4 抗体 (C-Term))

IHC

2 images

产品编号 ABIN6262681

发货至: 中国

Quick Overview for ITGA4 抗体 (C-Term) (ABIN6262681)

抗原

See all ITGA4 抗体

ITGA4 (Integrin alpha 4 (ITGA4))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This ITGA4 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Discover our top product ITGA4 Primary Antibody

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C-Term

特异性

Integrin alpha4 Antibody detects endogenous levels of total Integrin alpha4.

预测反应

Pig,Bovine,Horse,Sheep,Rabbit,Dog

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human Integrin alpha4, corresponding to a region within C-terminal amino acids.

亚型

IgG
anti-Integrin alpha 4 (ITGA4) (Internal Region) antibody
ITGA4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Integrin alpha 4 (ITGA4) antibody
ITGA4 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 5C4 unconjugated

anti-Integrin alpha 4 (ITGA4) (AA 551-650) antibody
ITGA4 适用: 人, 小鼠, 兔 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Integrin alpha 4 (ITGA4) (AA 833-977) antibody
ITGA4 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 7E4C5 unconjugated

anti-Integrin alpha 4 (ITGA4) (AA 376-558) antibody
ITGA4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Integrin alpha 4 (ITGA4) (C-Term) antibody
ITGA4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Integrin alpha 4 (ITGA4) antibody
ITGA4 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

anti-Integrin alpha 4 (ITGA4) antibody
ITGA4 适用: 人 FACS, WB, EIA 宿主: 小鼠 Monoclonal 5C4 unconjugated

anti-Integrin alpha 4 (ITGA4) antibody
ITGA4 适用: 小鼠 FACS, IP, IHC (fro), Func 宿主: 大鼠 Monoclonal DATK32 unconjugated

anti-Integrin alpha 4 (ITGA4) antibody
ITGA4 适用: 小鼠 FACS, IP, IHC (fro) 宿主: 大鼠 Monoclonal DATK32 unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

ITGA4 (Integrin alpha 4 (ITGA4))

别名

ITGA4

背景

Description: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. ITGA4:ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed:23125415). ITGA4:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877).
Gene: ITGA4

分子量

115kDa

基因ID

3676

UniProt

P13612

途径

Integrin Complex