Importin 5 抗体
Quick Overview for Importin 5 抗体 (ABIN6262636)
抗原
See all Importin 5 (IPO5) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- IPO5 Antibody detects endogenous levels of total IPO5
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human IPO5
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亚型
- IgG
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anti-Importin 5 (IPO5) (AA 1-100) antibody
IPO5 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Importin 5 (IPO5) (AA 20-300) antibodyIPO5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Importin 5 (IPO5) (AA 1-1115) antibodyIPO5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Importin 5 (IPO5) antibodyIPO5 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Importin 5 (IPO5) (AA 1-101) antibodyIPO5 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Importin 5 (IPO5) (N-Term) antibodyIPO5 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Importin 5 (IPO5) antibodyIPO5 适用: 人, 大鼠, 小鼠 WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
anti-Importin 5 (IPO5) (AA 143-192) antibodyIPO5 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- Importin 5 (IPO5)
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别名
- IPO5
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背景
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Description: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. Binds to CPEB3 and mediates its nuclear import following neuronal stimulation (By similarity). In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev.
Gene: IPO5
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分子量
- 123kDa
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基因ID
- 3843
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UniProt
- O00410
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途径
- Protein targeting to Nucleus
抗原
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