ITGA3 抗体
Quick Overview for ITGA3 抗体 (ABIN6262608)
抗原
See all ITGA3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Integrin α3 (CD49c) Antibody detects endogenous levels of total Integrin α3 (CD49c)
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交叉反应
- 人, 小鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Integrin alpha3 (CD49c)
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- ITGA3 (Integrin, alpha 3 (ITGA3))
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别名
- Integrin alpha3
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背景
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Description: Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Gene: ITGA3
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分子量
- 118 kDa
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基因ID
- 3675
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UniProt
- P26006
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途径
- CXCR4-mediated Signaling Events, Integrin Complex
抗原
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