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INSIG2 抗体 (N-Term)

This anti-INSIG2 antibody is a 兔 多克隆 antibody detecting INSIG2 in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6262600
发货至: 中国

Quick Overview for INSIG2 抗体 (N-Term) (ABIN6262600)

抗原

See all INSIG2 抗体
INSIG2 (Insulin Induced Gene 2 (INSIG2))

适用

  • 20
  • 15
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  • 2
  • 2
  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 30

克隆类型

  • 30
多克隆

标记

  • 9
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
This INSIG2 antibody is un-conjugated

应用范围

  • 22
  • 13
  • 13
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 3
    • 1
    • 1
    N-Term

    特异性

    INSIG2 Antibody detects endogenous levels of total INSIG2.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human INSIG2, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    INSIG2 (Insulin Induced Gene 2 (INSIG2))

    别名

    INSIG2

    背景

    Description: Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.

    Gene: INSIG2

    分子量

    25 kDa

    基因ID

    51141

    UniProt

    Q9Y5U4

    途径

    ER-Nucleus Signaling
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