IL28B 抗体
Quick Overview for IL28B 抗体 (ABIN6262561)
抗原
See all IL28B 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- IL28B Antibody detects endogenous levels of total IL28B
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human IL28B
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亚型
- IgG
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anti-Interleukin 28B (Interferon, lambda 3) (IL28B) (AA 22-196) antibody
IL28B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 28B (Interferon, lambda 3) (IL28B) antibodyIL28B 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 28B (Interferon, lambda 3) (IL28B) (AA 22-196) antibodyIL28B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 28B (Interferon, lambda 3) (IL28B) (AA 34-63), (N-Term) antibodyIL28B 适用: 人 WB 宿主: 兔 Polyclonal RB36625 unconjugated
anti-Interleukin 28B (Interferon, lambda 3) (IL28B) (AA 33-63), (N-Term) antibodyIL28B 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000 IHC 1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
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别名
- IL28B
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背景
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Description: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Gene: IFNL3
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分子量
- 22 kDa
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基因ID
- 282617
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UniProt
- Q8IZI9, Q8IZJ0
抗原
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