IFIT1 抗体 (Internal Region)
Quick Overview for IFIT1 抗体 (Internal Region) (ABIN6262448)
抗原
See all IFIT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- IFIT1 Antibody detects endogenous levels of total IFIT1.
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预测反应
- Horse
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human IFIT1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) (AA 1-181) antibody
IFIT1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) (AA 1-478) antibodyIFIT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) antibodyIFIT1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) (AA 1-478) antibodyIFIT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) (AA 1-478) antibodyIFIT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))
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别名
- IFIT1
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背景
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Description: Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.
Gene: IFIT1
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分子量
- 55kDa
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基因ID
- 3434
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UniProt
- P09914
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途径
- Hepatitis C
抗原
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