EIF3L 抗体 (N-Term)
Quick Overview for EIF3L 抗体 (N-Term) (ABIN6262447)
抗原
See all EIF3L 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- IF3EI Antibody detects endogenous levels of total IF3EI.
-
预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human IF3EI, corresponding to a region within N-terminal amino acids.
-
亚型
- IgG
-
-
anti-Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L) antibody
EIF3L 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L) (AA 1-230) antibodyEIF3L 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L) (N-Term) antibodyEIF3L 适用: 人, 小鼠, Cow, 犬, 小鸡, 猴, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L) (N-Term) antibodyEIF3L 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L) antibodyEIF3L 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L) (N-Term) antibodyEIF3L 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L) (N-Term) antibodyEIF3L 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡, 猴, Pig, 豚鼠, 马, 兔, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L) (AA 12-40), (N-Term) antibodyEIF3L 适用: 人 WB 宿主: 兔 Polyclonal RB41025 unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L) (N-Term) antibodyEIF3L 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))
-
别名
- EIF3L
-
背景
-
Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Gene: EIF3L
-
分子量
- 67kDa
-
基因ID
- 51386
-
UniProt
- Q9Y262
-
途径
- Ribonucleoprotein Complex Subunit Organization
抗原
-
