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Id2 抗体 (C-Term)

This anti-Id2 antibody is a 兔 多克隆 antibody detecting Id2 in ELISA, IHC 和 WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6262442
发货至: 中国

Quick Overview for Id2 抗体 (C-Term) (ABIN6262442)

抗原

See all Id2 抗体
Id2 (Inhibitor of DNA Binding 2 (Id2))

适用

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人, 大鼠, 小鼠

宿主

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  • 9
  • 1

克隆类型

  • 42
  • 8
多克隆

标记

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This Id2 antibody is un-conjugated

应用范围

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  • 4
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  • 1
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ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

    • 15
    • 13
    • 1
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    C-Term

    特异性

    ID2 Antibody detects endogenous levels of total ID2.

    预测反应

    Pig,Bovine,Horse,Sheep,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human ID2, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    Id2 (Inhibitor of DNA Binding 2 (Id2))

    别名

    ID2

    背景

    Description: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.

    Gene: ID2

    分子量

    18kDa

    基因ID

    3398

    UniProt

    Q02363
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