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HSPE1 抗体 (Internal Region)

This anti-HSPE1 antibody is a 兔 多克隆 antibody detecting HSPE1 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6262388
发货至: 中国

Quick Overview for HSPE1 抗体 (Internal Region) (ABIN6262388)

抗原

See all HSPE1 抗体
HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

适用

  • 108
  • 50
  • 39
  • 18
  • 16
  • 15
  • 15
  • 15
  • 15
  • 13
  • 13
  • 9
  • 3
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  • 2
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人, 小鼠, 大鼠

宿主

  • 129
  • 4
  • 2
  • 1

克隆类型

  • 121
  • 15
多克隆

标记

  • 47
  • 20
  • 13
  • 8
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This HSPE1 antibody is un-conjugated

应用范围

  • 99
  • 60
  • 51
  • 34
  • 32
  • 26
  • 26
  • 16
  • 13
  • 12
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 20
    • 15
    • 15
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    特异性

    HSP10 Antibody detects endogenous levels of total HSP10.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Rabbit,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human HSP10, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

    别名

    HSPE1

    背景

    Description: Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:7912672, PubMed:1346131, PubMed:11422376). The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable).

    Gene: HSPE1

    分子量

    10kDa

    基因ID

    3336

    UniProt

    P61604

    途径

    Positive Regulation of Endopeptidase Activity
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