CBX3 抗体 (Internal Region)
Quick Overview for CBX3 抗体 (Internal Region) (ABIN6262358)
抗原
See all CBX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- HP1 gamma Antibody detects endogenous levels of total HP1 gamma.
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预测反应
- Pig,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human HP1 gamma, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Chromobox Homolog 3 (CBX3) (Internal Region) antibody
Verified CBX3 适用: 人, 小鼠 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6D1C4 unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G12-1D9 unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 2-183) antibodyCBX3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) antibodyCBX3 适用: 人, 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) antibodyCBX3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (Middle Region) antibodyCBX3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- CBX3 (Chromobox Homolog 3 (CBX3))
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别名
- CBX3
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背景
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Description: Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1. Mediates the recruitement of NIPBL to sites of DNA damage at double-strand breaks (DSBs) (PubMed:28167679).
Gene: CBX3
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分子量
- 22kDa
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基因ID
- 11335
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UniProt
- Q13185
抗原
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