HORMAD1 抗体 (C-Term)
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Quick Overview for HORMAD1 抗体 (C-Term) (ABIN6262338)
抗原
See all HORMAD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- HORMAD1 Antibody detects endogenous levels of total HORMAD1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human HORMAD1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-HORMA Domain Containing 1 (HORMAD1) (AA 1-394) antibody
HORMAD1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-HORMA Domain Containing 1 (HORMAD1) (C-Term) antibodyHORMAD1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- HORMAD1 (HORMA Domain Containing 1 (HORMAD1))
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别名
- HORMAD1
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背景
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Description: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
Gene: HORMAD1
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分子量
- 45kDa
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基因ID
- 84072
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UniProt
- Q86X24
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途径
- M Phase
抗原
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