HMGB3 抗体 (Internal Region)
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Quick Overview for HMGB3 抗体 (Internal Region) (ABIN6262302)
抗原
See all HMGB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- HMGB3 Antibody detects endogenous levels of total HMGB3.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human HMGB3, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-High Mobility Group Box 3 (HMGB3) (AA 1-103) antibody
HMGB3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 62-95), (N-Term) antibodyHMGB3 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) antibodyHMGB3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 150-200) antibodyHMGB3 适用: 人, 小鼠, Cow, 犬, 马, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 1-200) antibodyHMGB3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (C-Term) antibodyHMGB3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig, 豚鼠, 斑马鱼, 小鸡, Hamster, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 14-176) antibodyHMGB3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) antibodyHMGB3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 100-200) antibodyHMGB3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) antibodyHMGB3 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- HMGB3 (High Mobility Group Box 3 (HMGB3))
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别名
- HMGB3
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背景
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Description: Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (By similarity).
Gene: HMGB3
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分子量
- 23 kDa
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基因ID
- 3149
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UniProt
- O15347
抗原
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