HIPK1 抗体 (N-Term)
Quick Overview for HIPK1 抗体 (N-Term) (ABIN6262240)
抗原
See all HIPK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- HIPK1 Antibody detects endogenous levels of total HIPK1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human HIPK1, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 330-430) antibody
HIPK1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 1007-1151) antibodyHIPK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) antibodyHIPK1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 330-430) antibodyHIPK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 1-100) antibodyHIPK1 适用: 人, 小鼠, 猴, Macaque WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 1043-1092) antibodyHIPK1 适用: 人, 小鼠, 大鼠, 猴, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 1-290) antibodyHIPK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 893-922), (C-Term) antibodyHIPK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB09623 unconjugated
anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 892-922), (C-Term) antibodyHIPK1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
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别名
- HIPK1
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背景
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Description: Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.
Gene: HIPK1
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分子量
- 131 kDa
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基因ID
- 204851
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UniProt
- Q86Z02
抗原
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