HEY1 抗体 (Internal Region)
Quick Overview for HEY1 抗体 (Internal Region) (ABIN6262226)
抗原
See all HEY1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- HEY1 Antibody detects endogenous levels of total HEY1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human HEY1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) (AA 121-220) antibody
HEY1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B3 unconjugated
anti-Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) (C-Term) antibodyHEY1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) (AA 50-150) antibodyHEY1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) (AA 200-300) antibodyHEY1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) antibodyHEY1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) (AA 1-304) antibodyHEY1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) (AA 181-288) antibodyHEY1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E5 unconjugated
anti-Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) (AA 181-288) antibodyHEY1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D1 unconjugated
anti-Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) (AA 180-229) antibodyHEY1 适用: 人, 大鼠, Cow, 犬, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) (AA 35-84) antibodyHEY1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Pig, 猴, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))
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别名
- HEY1
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背景
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Description: Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3 (PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737).
Gene: HEY1
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分子量
- 32-34 kDa
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基因ID
- 23462
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UniProt
- Q9Y5J3
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途径
- Tube Formation
抗原
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