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HDAC7 抗体 (C-Term)

This anti-HDAC7 antibody is a 兔 多克隆 antibody detecting HDAC7 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6262190
发货至: 中国

Quick Overview for HDAC7 抗体 (C-Term) (ABIN6262190)

抗原

See all HDAC7 抗体
HDAC7 (Histone Deacetylase 7 (HDAC7))

适用

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人, 小鼠

宿主

  • 108
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克隆类型

  • 100
  • 14
多克隆

标记

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This HDAC7 antibody is un-conjugated

应用范围

  • 75
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
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    C-Term

    特异性

    HDAC7 Antibody detects endogenous levels of total HDAC7.

    预测反应

    Horse,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human HDAC7, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    HDAC7 (Histone Deacetylase 7 (HDAC7))

    别名

    HDAC7

    背景

    Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).

    Gene: HDAC7

    分子量

    103 kDa

    基因ID

    51564

    UniProt

    Q8WUI4

    途径

    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
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