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HCFC1 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects HCFC1 in WB, IHC 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN6262160
发货至: 中国
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Quick Overview for HCFC1 抗体 (N-Term) (ABIN6262160)

抗原

See all HCFC1 抗体
HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

适用

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  • 25
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  • 4
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  • 1
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人, 小鼠, 大鼠

宿主

  • 37

克隆类型

  • 37
多克隆

标记

  • 26
  • 2
  • 2
  • 1
  • 1
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This HCFC1 antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term

    特异性

    HCFC1 Antibody detects endogenous levels of total HCFC1.

    预测反应

    Pig,Bovine,Horse,Rabbit,Dog,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human HCFC1, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

    别名

    HCFC1

    背景

    Description: Involved in control of the cell cycle (PubMed:10629049, PubMed:10779346, PubMed:15190068, PubMed:16624878, PubMed:23629655). Also antagonizes transactivation by ZBTB17 and GABP2, represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300 (PubMed:10675337, PubMed:12244100). Coactivator for EGR2 and GABP2 (PubMed:12244100, PubMed:14532282). Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription, respectively) together (PubMed:12670868). Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1 (PubMed:20200153). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Recruits KMT2E/MLL5 to E2F1 responsive promoters promoting transcriptional activation and thereby facilitates G1 to S phase transition (PubMed:23629655).

    Gene: HCFC1

    分子量

    209kDa

    基因ID

    3054

    UniProt

    P51610
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