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HAX1 抗体 (C-Term)

This anti-HAX1 antibody is a 兔 多克隆 antibody detecting HAX1 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6262152
发货至: 中国

Quick Overview for HAX1 抗体 (C-Term) (ABIN6262152)

抗原

See all HAX1 抗体
HAX1 (HCLS1 Associated Protein X-1 (HAX1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This HAX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    特异性

    HAX1 Antibody detects endogenous levels of total HAX1.

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human HAX1, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    HAX1 (HCLS1 Associated Protein X-1 (HAX1))

    别名

    HAX1

    背景

    Description: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex (PubMed:26997484). Slows down the rate of inactivation of KCNC3 channels (PubMed:26997484). Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.

    Gene: HAX1

    分子量

    31kDa

    基因ID

    10456

    UniProt

    O00165

    途径

    Regulation of Actin Filament Polymerization
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