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H3F3B 抗体 (N-Term)

This anti-H3F3B antibody is a 兔 多克隆 antibody detecting H3F3B in WB, ELISA, IF, IHC 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6262140
发货至: 中国

Quick Overview for H3F3B 抗体 (N-Term) (ABIN6262140)

抗原

See all H3F3B 抗体
H3F3B (H3 Histone, Family 3B (H3.3B) (H3F3B))

适用

  • 8
  • 4
  • 3
人, 小鼠

宿主

  • 7
  • 2

克隆类型

  • 8
  • 1
多克隆

标记

  • 9
This H3F3B antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • 抗原表位

    • 3
    • 1
    • 1
    • 1
    N-Term

    特异性

    H3F3A Antibody detects endogenous levels of total H3F3A.

    预测反应

    Pig,Zebrafish,Bovine,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human H3F3A, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    H3F3B (H3 Histone, Family 3B (H3.3B) (H3F3B))

    别名

    H3F3A, H3F3B

    背景

    Description: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Gene: H3F3A, H3F3B

    分子量

    19 kDa

    基因ID

    3020, 3021

    UniProt

    P84243
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