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GRIA4 抗体

This anti-GRIA4 antibody is a 兔 多克隆 antibody detecting GRIA4 in WB, ELISA, ICC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6262083
发货至: 中国

Quick Overview for GRIA4 抗体 (ABIN6262083)

抗原

See all GRIA4 抗体
GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 67
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多克隆

标记

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This GRIA4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 特异性

    GRIA4 Antibody detects endogenous levels of total GRIA4

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human GRIA4

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IF/ICC 1:100-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C.Stable for 12 months from date of receipt

    有效期

    12 months
  • 抗原

    GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

    别名

    GRIA4

    背景

    Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

    Gene: GRIA4

    分子量

    120 kDa

    基因ID

    2893

    UniProt

    P48058

    途径

    PI3K-Akt Signaling
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