Frataxin 抗体 (Internal Region)
Quick Overview for Frataxin 抗体 (Internal Region) (ABIN6261832)
抗原
See all Frataxin (FXN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- FXN Antibody detects endogenous levels of total FXN.
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预测反应
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human FXN, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Frataxin (FXN) (AA 57-210) antibody
FXN 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal FXN-2124 unconjugated
anti-Frataxin (FXN) (AA 42-210) antibodyFXN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 91-200) antibodyFXN 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3G9 unconjugated
anti-Frataxin (FXN) (AA 91-200) antibodyFXN 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-Frataxin (FXN) (AA 41-207) antibodyFXN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 36-64), (N-Term) antibodyFXN 适用: 人 WB 宿主: 兔 Polyclonal RB41914 unconjugated
anti-Frataxin (FXN) (AA 1-210) antibodyFXN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 1-210) antibodyFXN 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 105-154) antibodyFXN 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 犬, 豚鼠, 猴, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 72-102) antibodyFXN 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB12541 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Frataxin (FXN)
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别名
- FXN
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背景
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Description: Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization, however, the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1.
Gene: FXN
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分子量
- 23kDa
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基因ID
- 2395
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UniProt
- Q16595
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途径
- Transition Metal Ion Homeostasis, Regulation of Cell Size
抗原
-
