FTO 抗体 (C-Term)
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北京 101111
Quick Overview for FTO 抗体 (C-Term) (ABIN6261827)
抗原
See all FTO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- FTO Antibody detects endogenous levels of total FTO.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human FTO, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Fat Mass and Obesity-Associated (FTO) antibody
FTO 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Monoclonal 4G9 unconjugated Recombinant Antibody
anti-Fat Mass and Obesity-Associated (FTO) antibodyKO Validated FTO 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2700 unconjugated Recombinant Antibody
anti-Fat Mass and Obesity-Associated (FTO) antibodyKO Validated FTO 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3625 unconjugated Recombinant Antibody
anti-Fat Mass and Obesity-Associated (FTO) antibodyKO Validated FTO 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB3740 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 小鼠 WB, ELISA, IHC, IP 宿主: 小鼠 Monoclonal FT62-6 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人 WB, ELISA, IHC, IP 宿主: 小鼠 Monoclonal AG103 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) (AA 416-505) antibodyFTO 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人, 小鼠, 大鼠, 犬, Cow, 绵羊, 马, 灵长类 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5-2H10 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) (N-Term) antibodyFTO 适用: 人, 小鼠, 大鼠, Cow, 绵羊, Pig, 马, 猴, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- FTO (Fat Mass and Obesity-Associated (FTO))
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别名
- FTO
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背景
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Description: Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine (PubMed:18775698, PubMed:20376003). Specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:22002720, PubMed:26458103). Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation (PubMed:18775698, PubMed:20376003). In particular, it is involved in the regulation of thermogenesis and the control of adipocyte differentiation into brown or white fat cells (PubMed:26287746).
Gene: FTO
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分子量
- 58 kDa
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基因ID
- 79068
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UniProt
- Q9C0B1
抗原
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