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FTO 抗体 (C-Term)

This anti-FTO antibody is a 兔多克隆 antibody detecting FTO in WB, ELISA 和 IHC. Suitable for 人.

Western blot analysis FTO using Jurkat whole cell lysates (FTO 抗体 (C-Term))

1 image

产品编号 ABIN6261827

发货至: 中国

Datasheet as PDF

Quick Overview for FTO 抗体 (C-Term) (ABIN6261827)

抗原

See all FTO 抗体

FTO (Fat Mass and Obesity-Associated (FTO))

适用

62
27
25
5
4
4
4
4
2
1
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

35
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This FTO antibody is un-conjugated

应用范围

52
20
15
14
14
12
11
5
5
4
3
2
1

Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Discover our top product FTO Primary Antibody

抗原表位
15

12

6

1

1

1

1

1

1
C-Term

特异性

FTO Antibody detects endogenous levels of total FTO.

预测反应

Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human FTO, corresponding to a region within C-terminal amino acids.

亚型

IgG
anti-Fat Mass and Obesity-Associated (FTO) antibody
FTO 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Monoclonal 4G9 unconjugated Recombinant Antibody

anti-Fat Mass and Obesity-Associated (FTO) antibody
FTO 适用: 小鼠 WB, ELISA, IHC, IP 宿主: 小鼠 Monoclonal FT62-6 unconjugated

anti-Fat Mass and Obesity-Associated (FTO) antibody
FTO 适用: 人 WB, ELISA, IHC, IP 宿主: 小鼠 Monoclonal AG103 unconjugated

anti-Fat Mass and Obesity-Associated (FTO) antibody
FTO 适用: 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fat Mass and Obesity-Associated (FTO) antibody
FTO 适用: 人, 小鼠, 大鼠, 犬, Cow, 绵羊, 马, 灵长类 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 5-2H10 unconjugated

anti-Fat Mass and Obesity-Associated (FTO) antibody
FTO 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 小鼠 Monoclonal FT86-4 unconjugated

anti-Fat Mass and Obesity-Associated (FTO) (AA 416-505) antibody
FTO 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Fat Mass and Obesity-Associated (FTO) (N-Term) antibody
FTO 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 5-2H10 unconjugated

anti-Fat Mass and Obesity-Associated (FTO) (AA 1-30), (N-Term) antibody
FTO 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21572 unconjugated

anti-Fat Mass and Obesity-Associated (FTO) antibody
FTO 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

FTO (Fat Mass and Obesity-Associated (FTO))

别名

FTO

背景

Description: Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine (PubMed:18775698, PubMed:20376003). Specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:22002720, PubMed:26458103). Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation (PubMed:18775698, PubMed:20376003). In particular, it is involved in the regulation of thermogenesis and the control of adipocyte differentiation into brown or white fat cells (PubMed:26287746).
Gene: FTO

分子量

58 kDa

基因ID

79068

UniProt

Q9C0B1

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