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FFAR1 抗体 (Internal Region)

This anti-FFAR1 antibody is a 兔 多克隆 antibody detecting FFAR1 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6261716
发货至: 中国

Quick Overview for FFAR1 抗体 (Internal Region) (ABIN6261716)

抗原

See all FFAR1 抗体
FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

适用

  • 57
  • 29
  • 17
  • 5
  • 5
  • 3
  • 1
人, 小鼠, 大鼠

宿主

  • 57
  • 2
  • 1

克隆类型

  • 58
  • 2
多克隆

标记

  • 25
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FFAR1 antibody is un-conjugated

应用范围

  • 46
  • 17
  • 13
  • 13
  • 9
  • 8
  • 7
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 8
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    特异性

    GPR40 Antibody detects endogenous levels of total GPR40.

    预测反应

    Pig,Bovine,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human GPR40, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

    别名

    FFAR1

    背景

    Description: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

    Gene: FFAR1

    分子量

    31 kDa

    基因ID

    2864

    UniProt

    O14842

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
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