FAM65B 抗体
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北京 101111
Quick Overview for FAM65B 抗体 (ABIN6261669)
抗原
See all FAM65B 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- FAM65B antibody detects endogenous levels of FAM65B.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human FAM65B.
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亚型
- IgG
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anti-Family with Sequence Similarity 65, Member B (FAM65B) (AA 1-210) antibody
FAM65B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 65, Member B (FAM65B) (AA 1-591) antibodyFAM65B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6-1B10 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- FAM65B (Family with Sequence Similarity 65, Member B (FAM65B))
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别名
- FAM65B
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背景
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Description: Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization (PubMed:17150207, PubMed:24687993, PubMed:23241886, PubMed:24958875, PubMed:25588844, PubMed:27556504). Inhibits chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration (PubMed:23241886). Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion (By similarity). Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear (By similarity). Plays a role for maintaining the structural organization of the basal domain of stereocilia (By similarity). Involved in mechanosensory hair cell function (By similarity). Required for normal hearing (PubMed:24958875).
Gene: RIPOR2
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分子量
- 115 kDa,66 kDa
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基因ID
- 9750
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UniProt
- Q9Y4F9
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途径
- Transition Metal Ion Homeostasis
抗原
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