EYA2 抗体 (Internal Region)
Quick Overview for EYA2 抗体 (Internal Region) (ABIN6261629)
抗原
See all EYA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- EYA2 Antibody detects endogenous levels of total EYA2.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human EYA2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 164-271) antibody
EYA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 1-514) antibodyEYA2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 1-538) antibodyEYA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 200-249) antibodyEYA2 适用: 人, 大鼠, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 300-400) antibodyEYA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 216-244) antibodyEYA2 适用: 人 WB 宿主: 兔 Polyclonal RB37025 unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
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别名
- EYA2
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背景
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Description: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (PubMed:12500905, PubMed:23435380). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed:19351884). Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2, in this it is functionally redundant with EYA1 (PubMed:12500905).
Gene: EYA2
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分子量
- 59 kDa
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基因ID
- 2139
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UniProt
- O00167
抗原
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