ERAP1 抗体 (Internal Region)
Quick Overview for ERAP1 抗体 (Internal Region) (ABIN6261584)
抗原
See all ERAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- ERAP1 Antibody detects endogenous levels of total ERAP1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ERAP1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) (AA 642-941) antibody
ERAP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) antibodyERAP1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) (Internal Region) antibodyERAP1 适用: 人, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) (Internal Region) antibodyERAP1 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) (AA 832-941) antibodyERAP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H8 unconjugated
anti-Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) (Center) antibodyERAP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) (Internal Region) antibodyERAP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
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别名
- ERAP1
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背景
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Description: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.
Gene: ERAP1
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分子量
- 107 kDa
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基因ID
- 51752
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UniProt
- Q9NZ08
抗原
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