EIF3I 抗体 (C-Term)
Quick Overview for EIF3I 抗体 (C-Term) (ABIN6261483)
抗原
See all EIF3I 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- EIF3I Antibody detects endogenous levels of total EIF3I.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human EIF3I, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I) (AA 276-486) antibody
EIF3I 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I) (AA 226-325) antibodyEIF3I 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B10 unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I) (AA 1-323) antibodyEIF3I 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I) antibodyEIF3I 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I) (C-Term) antibodyEIF3I 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))
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别名
- EIF3I
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背景
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Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Gene: EIF3I
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分子量
- 36 kDa
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基因ID
- 8668
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UniProt
- Q13347
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Ribonucleoprotein Complex Subunit Organization, Synthesis of DNA
抗原
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