EHMT2 抗体 (N-Term)
Quick Overview for EHMT2 抗体 (N-Term) (ABIN6261470)
抗原
See all EHMT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- EHMT2 Antibody detects endogenous levels of total EHMT2.
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human EHMT2, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Ankyrin Repeat-Containing Protein (EHMT2) (AA 317-471) antibody
EHMT2 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2D12A11 unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (AA 877-1176) antibodyEHMT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (N-Term) antibodyEHMT2 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (AA 361-395) antibodyEHMT2 适用: 人 WB 宿主: 兔 Polyclonal RB51566 unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (AA 589-623) antibodyEHMT2 适用: 小鼠 WB 宿主: 兔 Polyclonal RB52371 unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (AA 144-193) antibodyEHMT2 适用: 人, 兔, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (N-Term) antibodyEHMT2 适用: 人, 小鼠, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (AA 159-186), (N-Term) antibodyEHMT2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB21114 unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) antibodyKD Validated EHMT2 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC, IP 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))
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别名
- EHMT2
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背景
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Description: Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. May also methylate histone H1. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53. Also methylates CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6, KLF12 and itself.
Gene: EHMT2
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分子量
- 132kDa
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基因ID
- 10919
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UniProt
- Q96KQ7
抗原
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