EHD1 抗体 (C-Term)
Quick Overview for EHD1 抗体 (C-Term) (ABIN6261469)
抗原
See all EHD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- EHD1 Antibody detects endogenous levels of total EHD1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human EHD1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-EH-Domain Containing 1 (EHD1) (N-Term) antibody
Verified EHD1 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-EH-Domain Containing 1 (EHD1) (AA 401-498) antibodyEHD1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EH-Domain Containing 1 (EHD1) antibodyEHD1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-EH-Domain Containing 1 (EHD1) antibodyEHD1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-EH-Domain Containing 1 (EHD1) (C-Term) antibodyEHD1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-EH-Domain Containing 1 (EHD1) (AA 410-438), (C-Term) antibodyEHD1 适用: 人 WB 宿主: 兔 Polyclonal RB32073 unconjugated
anti-EH-Domain Containing 1 (EHD1) (Middle Region) antibodyEHD1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- EHD1 (EH-Domain Containing 1 (EHD1))
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别名
- EHD1
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背景
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Description: ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes (PubMed:24019528). Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes (PubMed:15020713, PubMed:17233914, PubMed:20801876). Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth (By similarity). Plays a role in myoblast fusion (By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing (By similarity). Plays a role in the formation of the ciliary vesicle (CV), an early step in cilium biogenesis. Proposed to be required for the fusion of distal appendage vesicles (DAVs) to form the CV by recruiting SNARE complex component SNAP29. Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension. Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis (PubMed:25686250).
Gene: EHD1
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分子量
- 61 kDa
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基因ID
- 10938
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UniProt
- Q9H4M9
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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