EDEM1 抗体 (C-Term)
Quick Overview for EDEM1 抗体 (C-Term) (ABIN6261429)
抗原
See all EDEM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- EDEM1 Antibody detects endogenous levels of total EDEM1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human EDEM1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 559-656) antibody
EDEM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 46-128) antibodyEDEM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 146-195) antibodyEDEM1 适用: 人, 小鼠, Cow, 兔, 猴, Pig, 豚鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (N-Term) antibodyEDEM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (Center) antibodyEDEM1 适用: 人, 小鼠, 大鼠, Cow, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
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别名
- EDEM1
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背景
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Description: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.
Gene: EDEM1
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分子量
- 74 kDa
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基因ID
- 9695
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UniProt
- Q92611
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途径
- ER-Nucleus Signaling
抗原
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