E2F4 抗体
Quick Overview for E2F4 抗体 (ABIN6261411)
抗原
See all E2F4 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- E2F4 antibody detects endogenous levels of total E2F4
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交叉反应
- 人, 猴, 小鼠, 大鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human E2F4
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亚型
- IgG
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应用备注
- WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))
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别名
- E2F4
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背景
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Description: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Gene: E2F4
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分子量
- 44kDa
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基因ID
- 1874
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UniProt
- Q16254, Q15329
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
抗原
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