DUSP6 抗体 (C-Term)
Quick Overview for DUSP6 抗体 (C-Term) (ABIN6261386)
抗原
See all DUSP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- DUSP6 Antibody detects endogenous levels of total DUSP6.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human DUSP6, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:100, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
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别名
- DUSP6
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背景
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Description: Inactivates MAP kinases. Has a specificity for the ERK family (PubMed:9858808). Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity). Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain (By similarity).
Gene: DUSP6
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分子量
- 27kDa
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基因ID
- 1848
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UniProt
- Q16828
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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