Dynamin 1-Like 抗体 (C-Term)
Quick Overview for Dynamin 1-Like 抗体 (C-Term) (ABIN6261371)
抗原
See all Dynamin 1-Like (DNM1L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- DRP1 Antibody detects endogenous levels of total DRP1.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human DRP1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Dynamin 1-Like (DNM1L) (AA 69-213) antibody
DNM1L 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4A4C7 unconjugated
anti-Dynamin 1-Like (DNM1L) (AA 69-213) antibodyDNM1L 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4E11B11 unconjugated
anti-Dynamin 1-Like (DNM1L) (AA 1-710) antibodyDNM1L 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-Dynamin 1-Like (DNM1L) antibodyDNM1L 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-Dynamin 1-Like (DNM1L) antibodyDNM1L 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-Dynamin 1-Like (DNM1L) antibodyDNM1L 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Dynamin 1-Like (DNM1L) (AA 411-710) antibodyDNM1L 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1-Like (DNM1L) (AA 496-710) antibodyDNM1L 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1-Like (DNM1L) (pSer637) antibodyDNM1L 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1-Like (DNM1L) (N-Term) antibodyDNM1L 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Dynamin 1-Like (DNM1L)
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别名
- DNM1L
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背景
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Description: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis, this requirement may depend upon the cell type and the physiological apoptotic cues. Plays an important role in mitochondrial fission during mitosis (PubMed:26992161). Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles, the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution.
Gene: DNM1L
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分子量
- 79kDa
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基因ID
- 10059
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UniProt
- O00429
抗原
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