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DPP4 抗体 (C-Term)

This anti-DPP4 antibody is a 兔 多克隆 antibody detecting DPP4 in WB 和 IHC. Suitable for 人 和 小鼠.
产品编号 ABIN6261360
发货至: 中国

Quick Overview for DPP4 抗体 (C-Term) (ABIN6261360)

抗原

See all DPP4 抗体
DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

适用

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人, 小鼠

宿主

  • 92
  • 68
  • 13
  • 3
  • 1

克隆类型

  • 90
  • 85
  • 1
多克隆

标记

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This DPP4 antibody is un-conjugated

应用范围

  • 87
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 11
    • 9
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    C-Term

    特异性

    CD26 Antibody detects endogenous levels of total CD26.

    预测反应

    Pig,Bovine,Horse,Rabbit

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human CD26, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

    别名

    DPP4

    背景

    Description: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

    Gene: DPP4

    分子量

    55-60 kDa

    基因ID

    1803

    UniProt

    P27487

    途径

    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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