DOCK7 抗体 (N-Term)
Quick Overview for DOCK7 抗体 (N-Term) (ABIN6261348)
抗原
See all DOCK7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- DOCK7 Antibody detects endogenous levels of total DOCK7.
-
预测反应
- Pig,Bovine,Sheep,Rabbit,Dog
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human DOCK7, corresponding to a region within N-terminal amino acids.
-
亚型
- IgG
-
-
anti-Dedicator of Cytokinesis 7 (DOCK7) (AA 1440-1671) antibody
DOCK7 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dedicator of Cytokinesis 7 (DOCK7) (AA 1-624) antibodyDOCK7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
-
别名
- DOCK7
-
背景
-
Description: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
Gene: DOCK7
-
分子量
- 242kDa
-
基因ID
- 85440
-
UniProt
- Q96N67
抗原
-
