DNAJC3 抗体 (C-Term)
Quick Overview for DNAJC3 抗体 (C-Term) (ABIN6261337)
抗原
See all DNAJC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- DNAJC3 Antibody detects endogenous levels of total DNAJC3.
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预测反应
- Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human DNAJC3, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) (AA 1-234) antibody
DNAJC3 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 4D3-F2 unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) (AA 1-226) antibodyDNAJC3 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) (AA 277-496) antibodyDNAJC3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) (AA 270-462) antibodyDNAJC3 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) (AA 189-223) antibodyDNAJC3 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB57780 unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) (AA 1-234) antibodyDNAJC3 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))
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别名
- DNAJC3
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背景
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Description: Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
Gene: DNAJC3
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分子量
- 54 kDa
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基因ID
- 5611
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UniProt
- Q13217
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途径
- ER-Nucleus Signaling
抗原
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