DNAJB14 抗体 (C-Term)
-
- 抗原 See all DNAJB14 抗体
- DNAJB14 (DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14))
-
抗原表位
- C-Term
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This DNAJB14 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 特异性
- DNAJB14 Antibody detects endogenous levels of total DNAJB14.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human DNAJB14, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product DNAJB14 Primary Antibody
-
anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) (AA 1-244) antibody
DNAJB14 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) antibodyDNAJB14 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) (AA 1-120) antibodyDNAJB14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- DNAJB14 (DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14))
- 别名
- DNAJB14 (DNAJB14 产品)
- 别名
- Dnajb14 antibody, MGC153638 antibody, DKFZp468H1319 antibody, EGNR9427 antibody, PRO34683 antibody, 5730496F10Rik antibody, flj14281 antibody, DnaJ heat shock protein family (Hsp40) member B14 antibody, DnaJ (Hsp40) homolog, subfamily B, member 14 antibody, DnaJ heat shock protein family (Hsp40) member B14 S homeolog antibody, DNAJB14 antibody, dnajb14 antibody, Dnajb14 antibody, dnajb14.S antibody
- 背景
-
Description: Acts as a co-chaperone with HSPA8/Hsc70, required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway (PubMed:24732912). Acts by determining HSPA8/Hsc70's ATPase and polypeptide-binding activities (PubMed:24732912). Can also act independently of HSPA8/Hsc70: together with DNAJB12, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers (PubMed:27916661). While stabilization of nascent channel proteins is dependent on HSPA8/Hsc70, the process of oligomerization of channel subunits is independent of HSPA8/Hsc70 (PubMed:27916661). When overexpressed, forms membranous structures together with DNAJB12 and HSPA8/Hsc70 within the nucleus, the role of these structures, named DJANGOs, is still unclear (PubMed:24732912).
Gene: DNAJB14
- 分子量
- 43 kDa
- 基因ID
- 79982
- UniProt
- Q8TBM8
-
