DNAJA1 抗体 (C-Term)
Quick Overview for DNAJA1 抗体 (C-Term) (ABIN6261327)
抗原
See all DNAJA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- DNAJA1 Antibody detects endogenous levels of total DNAJA1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human DNAJA1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- DNAJA1 (DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1))
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别名
- DNAJA1
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背景
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Description: Co-chaperone for HSPA8/Hsc70 (PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (PubMed:24512202).
Gene: DNAJA1
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分子量
- 44 kDa
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基因ID
- 3301
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UniProt
- P31689
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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