DMPK 抗体 (N-Term)
Quick Overview for DMPK 抗体 (N-Term) (ABIN6261318)
抗原
See all DMPK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- DMPK Antibody detects endogenous levels of total DMPK.
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human DMPK, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Dystrophia Myotonica-Protein Kinase (DMPK) antibody
DMPK 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-629) antibodyDMPK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 303-420) antibodyDMPK 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 243-424) antibodyDMPK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (N-Term) antibodyDMPK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 323-372) antibodyDMPK 适用: 人, 小鼠, Cow, 犬, 豚鼠, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (Center) antibodyDMPK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-152) antibodyDMPK 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (Middle Region) antibodyDMPK 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-629) antibodyDMPK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
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别名
- DMPK
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背景
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Description: Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeostasis. Phosphorylates PLN, a regulator of calcium pumps and may regulate sarcoplasmic reticulum calcium uptake in myocytes. May also phosphorylate FXYD1/PLM which is able to induce chloride currents. May also play a role in synaptic plasticity.
Gene: DMPK
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分子量
- 70kDa
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基因ID
- 1760
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UniProt
- Q09013
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途径
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
抗原
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