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DLC1 抗体 (N-Term)

This anti-DLC1 antibody is a 兔 多克隆 antibody detecting DLC1 in IHC, WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6261308
发货至: 中国

Quick Overview for DLC1 抗体 (N-Term) (ABIN6261308)

抗原

See all DLC1 抗体
DLC1 (Deleted in Liver Cancer 1 (DLC1))

适用

  • 37
  • 9
  • 8
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 35
  • 2
  • 1

克隆类型

  • 38
多克隆

标记

  • 17
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DLC1 antibody is un-conjugated

应用范围

  • 13
  • 13
  • 10
  • 9
  • 6
  • 6
  • 6
  • 3
  • 2
Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    DLC1 Antibody detects endogenous levels of total DLC1.

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human DLC1, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    DLC1 (Deleted in Liver Cancer 1 (DLC1))

    别名

    DLC1

    背景

    Description: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.

    Gene: DLC1

    分子量

    171kDa

    基因ID

    10395

    UniProt

    Q96QB1

    途径

    Tube Formation, Positive Regulation of Endopeptidase Activity
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