Cyclin C 抗体 (C-Term)
Quick Overview for Cyclin C 抗体 (C-Term) (ABIN6261144)
抗原
See all Cyclin C (CCNC) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- Cyclin C Antibody detects endogenous levels of total Cyclin C.
-
预测反应
- Bovine,Horse,Sheep,Rabbit,Chicken
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human Cyclin C, corresponding to a region within C-terminal amino acids.
-
亚型
- IgG
-
-
anti-Cyclin C (CCNC) (AA 1-283) antibody
CCNC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (AA 240-283) antibodyCCNC 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (AA 23-100) antibodyCCNC 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) antibodyCCNC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (AA 1-30) antibodyCCNC 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (Ser275) antibodyCCNC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (AA 1-30), (N-Term) antibodyCCNC 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB14994 unconjugated
anti-Cyclin C (CCNC) (AA 234-283), (pSer275) antibodyCCNC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (AA 1-30), (N-Term) antibodyCCNC 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (AA 221-249) antibodyCCNC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- Cyclin C (CCNC)
-
别名
- CCNC
-
背景
-
Description: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
Gene: CCNC
-
分子量
- 33 kDa
-
基因ID
- 892
-
UniProt
- P24863
-
途径
- Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
抗原
-
